Preservation of Gametes 

The Science of Life at Gynatal Timișoara 

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Vitrification Technology: Freezing Without Crystals Fertility Preservation Medical vs. Social Freezing
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Preservation of gametes (conservarea gameților) at Gynatal Clinic utilizes the advanced Vitrification method—ultra-rapid freezing at -196 °C. This technique effectively "stops time" for oocytes and sperm with a survival rate exceeding 95%. It is the "Scientific Gold Standard" for oncological patients and women choosing Social Freezing, allowing for the secure delay of parenthood without the degradation of genetic quality. 

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Vitrification Technology: Freezing Without Crystals

Unlike traditional slow-freezing methods of the past, Gynatal exclusively employs Vitrification. 

  • Speed: Cells are cooled at a rate higher than 15,000 °C per minute. 

  • Safety: This rapid transition bypasses the cooling plateau where ice crystals form, preventing damage to delicate cellular membranes. 

  • Success: The rata de supraviețuire (survival rate) after thawing is over 95%, maintaining a developmental potential nearly identical to fresh cells. 

Fertility Preservation

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Oocyte Preservation (Egg Freezing)

Egg freezing is a critical intervention, as female fertility and egg quality decline significantly after the age of 35. 
The Collection and Freezing Process 

  1. Hormonal Stimulation: A personalized 10–12 day protocol to stimulate the growth of multiple follicles. 
  2. Follicular Puncture: Egg retrieval is performed under sedation (anesthesia) and typically lasts 15–20 minutes. 
  3. Vitrification: Mature oocytes are immediately vitrified and stored in liquid nitrogen. 
The Ideal Timing 
Gynatal recommends retrieval before the age of 35, when oocyte quality is at its peak. Statistically, a 30-year-old may only need 6 frozen eggs for a high probability of future success, whereas a woman over 40 may require significantly more to account for natural chromosomal aging. 

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Sperm Preservation (Sperm Freezing)

Sperm freezing is a non-invasive, straightforward process that secures male reproductive potential. 

  • Indications: Recommended before oncological treatments, urological surgeries, high-risk occupations, or as a "back-up" on the day of a partner's egg retrieval. 
  • Preparation: A period of sexual abstinence for 2 to 5 days is required for optimal sample quality. 
  • Mandatory Screening: Before storage, patients must undergo mandatory screening for infectious diseases (HIV, Hepatitis B/C, VDRL). 

Medical vs. Social Freezing 

At Gynatal, we distinguish between two primary pathways for preservation: 

  1. Social Freezing: Elective preservation for personal or professional reasons (career, education, or currently lacking a partner). 

  1. Medical Preservation (Onco-fertility): Urgent preservation before starting chemotherapy or radiotherapy, which can irreversibly damage gametes. Gynatal offers fast-track protocols for oncological cases to ensure no delay in primary treatment. 

 

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Preservation Costs at Gynatal

  • Social OVO Freezing Package: Includes retrieval, vitrification, and the first 12 months of storage. 
  • Sperm Freezing: Simple, one-time freezing procedure. 
  • Annual Storage: Fee applied starting from the second year to maintain the cryogenic environment. 
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